In the face of changing climates and growing populations, high-precision, long read sequencing technology is enabling plant and animal scientists to gain actionable genomic insights that no other technology can provide. CD Genomics is a leading provider of customized solutions for long read sequencing, dedicated to capturing biodiversity, advancing agriculture, and improving gene editing workflows.
Plant genomes contain important information for understanding their structure. Resolving plant genome structure is key to unraveling the complex framework of genetic factors that determine phenotypic traits. High-quality reference genome assemblies are critical for accelerating plant breeding through the selection of desirable genes with improved agronomic traits, including high yields, tolerance to various environmental stresses, and resistance to pathogens. Animal genomics research can provide invaluable insights into many areas of scientific research by completing the construction of whole-genome sequence maps of these animals and using them as the centerpiece for a range of gene annotation, species evolution, and other studies that can provide the foundation for in-depth research in areas such as human disease research, animal environmental adaptation and evolution, species diversity conservation, and climate change.
Animal and plant genomes generated by Sanger and next-generation sequencing (NGS) provide insights into species diversity and evolution. However, the application of Sanger sequencing is limited due to high cost, labor intensity, and low throughput, while NGS reads are too short to resolve abundant repeats and polyploids, resulting in incomplete or ambiguous assemblies. The emergence and improvement of long read sequencing with third-generation sequencing methods, such as PacBio and Nanopore, show promise in producing high-quality assemblies of complex genomes in animals and plants.
Fig. 1. Plant genome project workflow from DNA extraction over Oxford Nanopore Technologies (ONT) sequencing to data submission. (Pucker et al., 2022)
Our long read sequencing solutions provide novel and cost-effective insights into animal genomes, transcriptomes, and microbiomes by precisely resolving complex genomic regions, haplotypes, and full-length transcripts. Direct sequencing of natural DNA or RNA further allows for the simultaneous identification of base modifications and nucleotide sequences.
Our long read sequencing provides long reads that can accurately assemble large, highly repetitive plant genomes and resolve structural variants, transposons, and transgene insertions, thus providing new insights into plant biology, evolution, and breeding strategies. Base modifications can be identified along with nucleotide sequences without additional experimental steps or costs, and the facility to sequence full-length transcripts supports enhanced gene annotation and gene expression studies.
Our long read sequencing is used in the following areas of plant and animal research.
Climate change and rapid global population growth are putting increasing pressure on world food production. Long read sequencing is being used in large-scale agricultural programs to help increase crop yields and control pests and diseases to meet the growing demand for agriculture. Whether your focus is crop or livestock breeding, genetic engineering, or pest control, our long-read sequencing solutions provide genomic data of exceptional quality and detail to meet the needs of your agricultural genomics research program. We aim to drive agricultural innovation like never before.
Climate change, pollution, and habitat loss are leading to global species loss and biodiversity degradation. Based on our long-read sequencing technology platform, CD Genomics offers powerful multi-omics solutions to explore biological complexity and provide the best possible data for conservation programs. This enables you to better capture genetic diversity by deciphering complex structural variation and single nucleotide polymorphisms in easily assembled, fixed-phase reference quality genomes. The combination of detailed multi-omics information ensures that biodiversity experts can better understand the ecological and conservation needs of any species, and may even hold promise for improving human health through bioprospecting and can be used as a means of preventing extinction.
CD Genomics is committed to exploiting the potential of long read sequencing to ensure that our customers remain at the forefront of animal and plant research. If you have any questions, please feel free to contact us. We look forward to working with you on projects of interest.
PacBio SMRT Sequencing
Oxford Nanopore Sequencing
Animal and Plant Genomics with Long-Read Sequencing
Animal/Plant Whole Genome De Novo Sequencing
Animal/Plant Whole Genome Sequencing
Animal/Plant RNA Sequencing
For research purposes only, not intended for personal diagnosis, clinical testing, or health assessment