Bacterial whole-genome resequencing involves sequencing the entire genome of a bacterium and comparing the sequencing reads to a known reference. CD Genomics is a leading custom service provider in sequencing technologies, particularly in the field of long-read sequencing. Our bacterial whole-genome resequencing service enables the analysis of multiple genomic variation types among microbial strains, providing accurate and in-depth information on bacterial genome sequences. With world-leading equipment combined with cutting-edge sequencing technology, we continue to help researchers gain new insights into bacteriology.
Whole-genome resequencing is a powerful tool to study bacterial genomes. So far, this method has helped researchers detect mutations in genetic suppressor screens, infer genome replication status, and identify base-pair substitutions, short insertions/deletions, and structural variants in genome instability studies. To perform whole-genome resequencing, Illumina sequencing has become the most straightforward and widely used approach. As the study of bacterial genetics continues, the shortcomings of this technology have become increasingly apparent. The Illumina platform has read lengths between 50-300 bp, which makes it very difficult to perform de novo assembly of the genome through repetitive genomic regions. The long-read sequencing platform overcomes the challenges related to short Illumina reads by significantly increasing read length. In addition, the ability of long-read sequencing to directly detect DNA base modifications without prior knowledge of their existence makes it an excellent tool to promote our understanding of a wide range of topics in bacteriology.
|Standard Analysis||Advanced Analysis|
|The removal of the sequencing adapters and low-quality sequences||Comparative genome analysis|
|Data QC||Gene synteny analysis|
|Reference genome alignment||Phylogenetic analysis|
|Genetic variation detection, annotation, and statistics, including SNP/InDel, CNV, SV||Customized analysis|
Whole-genome resequencing has multiple applications in bacteriology. Our services provide rapid and accurate bacterial genome sequence information to guide and inform screening for superior traits and strain resistance studies. Our customer service representatives are available 24 hours a day from Monday to Sunday. Let's know what your goals are and our team of experts will contact you within one business day to discuss your needs.